{"id":1367,"date":"2020-04-29T12:03:40","date_gmt":"2020-04-29T12:03:40","guid":{"rendered":"http:\/\/www.aassie.net\/Pro\/?p=1367"},"modified":"2022-02-08T16:07:09","modified_gmt":"2022-02-08T16:07:09","slug":"new-paper-out","status":"publish","type":"post","link":"https:\/\/www.aassie.net\/Pro\/new-paper-out\/","title":{"rendered":"CeMbio, a Microbiome in a kit ! A New Paper out"},"content":{"rendered":"[vc_row type=&#8221;in_container&#8221; full_screen_row_position=&#8221;middle&#8221; column_margin=&#8221;default&#8221; column_direction=&#8221;default&#8221; column_direction_tablet=&#8221;default&#8221; column_direction_phone=&#8221;default&#8221; scene_position=&#8221;center&#8221; text_color=&#8221;dark&#8221; text_align=&#8221;left&#8221; row_border_radius=&#8221;none&#8221; row_border_radius_applies=&#8221;bg&#8221; overlay_strength=&#8221;0.3&#8243; gradient_direction=&#8221;left_to_right&#8221; shape_divider_position=&#8221;bottom&#8221; bg_image_animation=&#8221;none&#8221;][vc_column column_padding=&#8221;no-extra-padding&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;all&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;1\/1&#8243; tablet_width_inherit=&#8221;default&#8221; tablet_text_alignment=&#8221;default&#8221; phone_text_alignment=&#8221;default&#8221; column_border_width=&#8221;none&#8221; column_border_style=&#8221;solid&#8221; bg_image_animation=&#8221;none&#8221;][image_with_animation image_url=&#8221;1372&#8243; animation=&#8221;Fade In&#8221; hover_animation=&#8221;none&#8221; alignment=&#8221;&#8221; border_radius=&#8221;none&#8221; box_shadow=&#8221;none&#8221; image_loading=&#8221;default&#8221; max_width=&#8221;100%&#8221; max_width_mobile=&#8221;default&#8221;][vc_column_text]I am happy to announce that the first\u00a0 paper out of my Postdoc in Houston is out!<\/p>\n<p>This project was an intense collaborative paper that defines a simple 12-member <em>C. elegans<\/em> microbiome\u00a0resource (#CeMbio) for the community. The collaboration was\u00a0between the Christian-Albrechts University (Kiel, Germany), the Ecole Normale Sup\u00e9rieure, (Paris, France), the University of California, Berkeley (CA, USA) and Baylor College of Medicine. The aim is to offer the <em>C. elegans<\/em> and the wider microbiome community with a community set composed of twelve fully characterized bacteria as a benchmark tool for host-microbe interactions studies.<\/p>\n<p>These 12 strains were selected to be representative (10\/12 core\u00a0#microbiome\u00a0families, &gt;65% of diversity), meaningful (isolated from natural worms\/ habitats\/ mesocosms), &amp; easy to use (all grow on LB).<\/p>\n<p>The CeMbio joins model\u00a0microbiomes across systems, from mice to\u00a0drosophila to\u00a0zebrafish to\u00a0arabidopsis and beyond, to find mechanisms of impact on health and\u00a0disease. This sandbox research system offers limitless possibility and offers a common and framework to compare the effect of the microbiome on different aspects of the host life, from life span to resistance to pathogens, to the effect on development and more.<\/p>\n<p style=\"text-align: center;\">You can access the paper by clicking the button below, and because it&#8217;s not every day you get a paper out it&#8217;s an extra big button!<\/p>\n[\/vc_column_text][vc_row_inner content_placement=&#8221;middle&#8221; column_margin=&#8221;default&#8221; column_direction=&#8221;default&#8221; column_direction_tablet=&#8221;default&#8221; column_direction_phone=&#8221;default&#8221; text_align=&#8221;center&#8221; css=&#8221;.vc_custom_1588286043161{margin-top: 2% !important;}&#8221;][vc_column_inner column_padding=&#8221;no-extra-padding&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;all&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;1\/4&#8243; tablet_width_inherit=&#8221;default&#8221; column_border_width=&#8221;none&#8221; column_border_style=&#8221;solid&#8221; bg_image_animation=&#8221;none&#8221;][\/vc_column_inner][vc_column_inner column_padding=&#8221;no-extra-padding&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;all&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;1\/2&#8243; tablet_width_inherit=&#8221;default&#8221; column_border_width=&#8221;none&#8221; column_border_style=&#8221;solid&#8221; bg_image_animation=&#8221;none&#8221;][nectar_btn size=&#8221;extra_jumbo&#8221; open_new_tab=&#8221;true&#8221; button_style=&#8221;regular-tilt&#8221; button_color=&#8221;Extra-Color-1&#8243; icon_family=&#8221;none&#8221; text=&#8221;CHECK OUT THE PREPRINT&#8221; url=&#8221;https:\/\/www.biorxiv.org\/content\/10.1101\/2020.04.22.055426v1.article-metrics&#8221; css_animation=&#8221;shake&#8221; margin_top=&#8221;2%&#8221; margin_left=&#8221;2%&#8221;][\/vc_column_inner][vc_column_inner column_padding=&#8221;no-extra-padding&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;all&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;1\/4&#8243; tablet_width_inherit=&#8221;default&#8221; column_border_width=&#8221;none&#8221; column_border_style=&#8221;solid&#8221; bg_image_animation=&#8221;none&#8221;][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row type=&#8221;in_container&#8221; full_screen_row_position=&#8221;middle&#8221; column_margin=&#8221;default&#8221; column_direction=&#8221;default&#8221; column_direction_tablet=&#8221;default&#8221; column_direction_phone=&#8221;default&#8221; scene_position=&#8221;center&#8221; text_color=&#8221;dark&#8221; text_align=&#8221;left&#8221; row_border_radius=&#8221;none&#8221; row_border_radius_applies=&#8221;bg&#8221; overlay_strength=&#8221;0.3&#8243; gradient_direction=&#8221;left_to_right&#8221; shape_divider_position=&#8221;bottom&#8221; bg_image_animation=&#8221;none&#8221;][vc_column column_padding=&#8221;no-extra-padding&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;all&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;1\/2&#8243; tablet_width_inherit=&#8221;default&#8221; tablet_text_alignment=&#8221;default&#8221; phone_text_alignment=&#8221;default&#8221; column_border_width=&#8221;none&#8221; column_border_style=&#8221;solid&#8221; bg_image_animation=&#8221;none&#8221;][vc_text_separator title=&#8221;Highlights of the community&#8221; title_align=&#8221;separator_align_left&#8221; color=&#8221;orange&#8221; border_width=&#8221;2&#8243; el_width=&#8221;80&#8243; css=&#8221;.vc_custom_1588284739939{margin-top: 2% !important;}&#8221;]<div class=\"nectar-fancy-ul\" data-list-icon=\"icon-salient-thin-line\" data-animation=\"false\" data-animation-delay=\"0\" data-color=\"accent-color\" data-spacing=\"default\" data-alignment=\"left\"> \n<ul>\n<li>All colonize the worm gut alone and come together to form a robust #microbiome, also influenced by host #genetics and #diet.<\/li>\n<li>Tons of resources, including genomes and metabolic models<\/li>\n<li>Each have different impacts on host physiology (e.g., faster growth)<\/li>\n<li>Easy to start (only 12 strains to test) and unlimited combos (12!, or nearly 480 million)<\/li>\n<\/ul>\n <\/div>[\/vc_column][vc_column column_padding=&#8221;no-extra-padding&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;all&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;1\/2&#8243; tablet_width_inherit=&#8221;default&#8221; tablet_text_alignment=&#8221;default&#8221; phone_text_alignment=&#8221;default&#8221; column_border_width=&#8221;none&#8221; column_border_style=&#8221;solid&#8221; bg_image_animation=&#8221;none&#8221;][vc_text_separator title=&#8221;A Microbiome in a Kit&#8221; title_align=&#8221;separator_align_right&#8221; color=&#8221;orange&#8221; border_width=&#8221;2&#8243; el_width=&#8221;80&#8243; css=&#8221;.vc_custom_1588284796501{margin-top: 2% !important;}&#8221;][vc_column_text]We made sure that whoever wants to play with the system can access it. All the bacterial strains are publicly available at the CGC (link below). And we encourage people to check the wiki <a href=\"http:\/\/www.cembio.uni-kiel.de\/\">here<\/a> to get extra advice on how to handle the kit, as well as to join the <em>C. elegans<\/em> slack and join the host-microbe channel to ask questions and share experiences.<\/p>\n<p><strong>ORDER STRAINS<\/strong> \u2014\u00a0<a href=\"https:\/\/cgc.umn.edu\/\" data-attribute-index=\"23\">https:\/\/cgc.umn.edu\/<\/a>[\/vc_column_text][\/vc_column][\/vc_row]\n","protected":false},"excerpt":{"rendered":"<p>[vc_row type=&#8221;in_container&#8221; full_screen_row_position=&#8221;middle&#8221; column_margin=&#8221;default&#8221; column_direction=&#8221;default&#8221; column_direction_tablet=&#8221;default&#8221; column_direction_phone=&#8221;default&#8221; scene_position=&#8221;center&#8221; text_color=&#8221;dark&#8221; text_align=&#8221;left&#8221; row_border_radius=&#8221;none&#8221; row_border_radius_applies=&#8221;bg&#8221; overlay_strength=&#8221;0.3&#8243; gradient_direction=&#8221;left_to_right&#8221; shape_divider_position=&#8221;bottom&#8221; bg_image_animation=&#8221;none&#8221;][vc_column column_padding=&#8221;no-extra-padding&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;all&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;1\/1&#8243; tablet_width_inherit=&#8221;default&#8221; tablet_text_alignment=&#8221;default&#8221; phone_text_alignment=&#8221;default&#8221; column_border_width=&#8221;none&#8221; column_border_style=&#8221;solid&#8221; bg_image_animation=&#8221;none&#8221;][image_with_animation image_url=&#8221;1372&#8243; animation=&#8221;Fade In&#8221; hover_animation=&#8221;none&#8221; alignment=&#8221;&#8221; border_radius=&#8221;none&#8221; box_shadow=&#8221;none&#8221; image_loading=&#8221;default&#8221; max_width=&#8221;100%&#8221; max_width_mobile=&#8221;default&#8221;][vc_column_text]I am happy to announce that the&#8230;<\/p>\n","protected":false},"author":2,"featured_media":1372,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[21,90],"tags":[11,99,51,30],"_links":{"self":[{"href":"https:\/\/www.aassie.net\/Pro\/wp-json\/wp\/v2\/posts\/1367"}],"collection":[{"href":"https:\/\/www.aassie.net\/Pro\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.aassie.net\/Pro\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.aassie.net\/Pro\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.aassie.net\/Pro\/wp-json\/wp\/v2\/comments?post=1367"}],"version-history":[{"count":11,"href":"https:\/\/www.aassie.net\/Pro\/wp-json\/wp\/v2\/posts\/1367\/revisions"}],"predecessor-version":[{"id":1379,"href":"https:\/\/www.aassie.net\/Pro\/wp-json\/wp\/v2\/posts\/1367\/revisions\/1379"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.aassie.net\/Pro\/wp-json\/wp\/v2\/media\/1372"}],"wp:attachment":[{"href":"https:\/\/www.aassie.net\/Pro\/wp-json\/wp\/v2\/media?parent=1367"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.aassie.net\/Pro\/wp-json\/wp\/v2\/categories?post=1367"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.aassie.net\/Pro\/wp-json\/wp\/v2\/tags?post=1367"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}